Pre-implantation Genetic Screening (PGS) is a last generation genetic test that permits us to screen for chromosomal idiosyncrasies on embryos in the course of an IVF cycle. The procedure involves a small biopsy on the embryos on which the analysis is performed. The test analyses all 24 chromosome types using array Comparative Genomic Hybridisation (aCGH), in order to identify aneuploidies (alterations in the number of chromosomes) and handpick chromosomally normal embryos for transfer. Those are most likely to develop to the complete term and be born as a healthy baby.
At MAGS, we recommend PGS in case:
- The patient is over 35 and has a higher risk of pregnancy with a chromosome
- The patient has a family history of chromosome problems
- The patient has a history of repeated miscarriages
- The patient has several unsuccessful cycles of IVF
- The patient’s husband is identified to have a high risk of having chromosome problems
The chromosome aneuploidies most commonly cause side effects such as Edwards’s syndrome, Down syndrome and Patau syndrome.